Hislop T G, Coldman A J, Zheng Y Y, Ng V T, Labo T
Division of Epidemiology, Biometry, and Occupational Oncology, British Columbia Cancer Agency, Vancouver, Canada.
Nutr Cancer. 1992;18(2):123-9. doi: 10.1080/01635589209514212.
A self-administered food frequency questionnaire was included as part of a case-control study of breast cancer in 1980-82. In 1986-87, a second food frequency questionnaire was sent to surviving cases and husbands of deceased cases; 30 spouses (86% response rate) and 263 surviving cases (88% response rate) returned questionnaires. The dietary questions concerned consumption of specific food items by the case before diagnosis of breast cancer. Missing values were less common in the second questionnaire; there was no significant difference in missing values between surviving cases and spouses of deceased cases. Kappa statistics comparing responses in the first and second questionnaires were significantly lower for spouses of deceased cases than for surviving cases. Reported level of confidence by the husbands regarding knowledge about their wives' eating habits did not influence the kappa statistics or the frequencies of missing values. The lack of good agreement has important implications for the use of proxy interviews from husbands in retrospective dietary studies.
一份自填式食物频率问卷作为1980 - 1982年乳腺癌病例对照研究的一部分被纳入。1986 - 1987年，第二份食物频率问卷被寄给存活病例以及已故病例的丈夫；30名配偶（回复率86%）和263名存活病例（回复率88%）返回了问卷。饮食问题涉及病例在被诊断出乳腺癌之前特定食物的摄入量。在第二份问卷中缺失值不太常见；存活病例和已故病例的配偶之间在缺失值方面没有显著差异。比较第一份和第二份问卷中回复情况的卡帕统计量，已故病例的配偶显著低于存活病例。丈夫报告的对其妻子饮食习惯了解程度的置信水平并未影响卡帕统计量或缺失值的频率。缺乏良好的一致性对在回顾性饮食研究中使用来自丈夫的代理访谈有重要影响。
