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[煤矽肺的当前模式、其并发症及与其他疾病的相关性(对1977 - 1988年300例法定尸检的评估)]

[Current pattern of anthracosilicosis, its complications and correlation with other diseases (evaluation of 300 legal autopsies 1977-1988)].

作者信息

Hartung W, Moon J S

机构信息

Institut für Pathologie, Ruhr-Universität, Bochum.

出版信息

Pneumologie. 1992 Oct;46(10):516-24.

PMID:1438124
Abstract

The spectrum of silicosis of coal miners has changed during the past decades. The life expectancy of the miners suffering from silicosis has been successfully adapted to that of the non-miners as a result of a consistent therapy. Morphologically, the processes involving large callosities have receded markedly; in their place, there has been an increased incidence of generalised focal dust emphysema that are difficult to differentiate clinically from the common chronic obstructive pulmonary diseases. Chronic bronchitis and emphysema are the most important concomitant pulmonary diseases; the incidence of tuberculosis is still enhanced and carcinomas of the lung are only rarely to be acknowledged as so-called carcinomas in scar tissue. Other major diseases that coincide with silicosis are seen in p.m. statistics with customary frequency of incidence (cardiovascular diseases almost 50%, malignant tumours including those of the lung about 25%, other major diseases without respiratory organs about 10%). The main problem in expertising is to differentiate the influence of these diseases from those of silicosis; expertising must employ the legally prescribed terminology. In our own investigations based on 300 postmortem expertises, death as a result of a professionally acquired disease was acknowledged in 48% of all cases of silicosis of severity grades I to III, silicosis being the sole major disease in only half of the cases and in the other cases an essential partial contributor to the cause of death. The significance of the extended generalised dust emphysema as a special type of pneumoconioses that must be classified as grave, is emphasised in contrast to previously compiled statistics.

摘要

在过去几十年中,煤矿工人矽肺的疾病谱发生了变化。由于采用了持续的治疗方法,患矽肺矿工的预期寿命已成功地与非矿工的预期寿命相适应。从形态学上看,涉及大硬结的病变已明显消退;取而代之的是,弥漫性局灶性尘性肺气肿的发病率有所增加,临床上难以将其与常见的慢性阻塞性肺疾病区分开来。慢性支气管炎和肺气肿是最重要的伴发肺部疾病;肺结核的发病率仍然较高,而肺癌仅在极少数情况下被认为是所谓的瘢痕组织癌。与矽肺同时发生的其他主要疾病,在尸检统计中以通常的发病率出现(心血管疾病近50%,包括肺癌在内的恶性肿瘤约25%,无呼吸器官的其他主要疾病约10%)。专家鉴定中的主要问题是区分这些疾病与矽肺的影响;专家鉴定必须采用法定规定的术语。在我们基于300例尸检专家鉴定的调查中,在所有I至III级矽肺病例中,48%的病例被认定为死于职业性获得的疾病,矽肺仅是半数病例中的唯一主要疾病,而在其他病例中则是导致死亡的重要部分原因。与以前汇编的统计数据相比,强调了广泛性弥漫性尘性肺气肿作为一种必须归类为严重的特殊类型尘肺病的重要性。

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