Fisseler-Eckhoff A, Heimberger K, Reitemeyer E, Müller K M
Institut f. Pathologie d. Berufsgenossenschaftlichen Krankenanstalten, Bergmannsheil Bochum, Universitätsklinik Bochum.
Pneumologie. 1990 Feb;44 Suppl 1:325-6.
In the diagnosis of a so-called scar carcinoma, one of the accepted morphological characteristics is the deposition of dust in tumours of the lung. In 50 bronchial carcinomas in former miners and patients not occupationally exposed to dust, the cause and significance of such lesions were investigated in autopsy and surgical material. Impregnation with dust must be considered to be a secondary phenomenon of the infiltrative tumour growth. Such depositions depend upon previously present dust depositions in the pulmonary parenchyma and on the localisation of the tumour, and reveal a clear correlation with the histological type and degree of differentiation of the tumour.
在所谓瘢痕癌的诊断中,公认的形态学特征之一是肺部肿瘤中有粉尘沉积。对50例曾为矿工及无职业粉尘接触史患者的支气管癌尸检和手术材料,研究了此类病变的病因及意义。粉尘沉着必须视为浸润性肿瘤生长的一种继发现象。这种沉积取决于肺实质中先前存在的粉尘沉积以及肿瘤的位置,并与肿瘤的组织学类型和分化程度明显相关。