Buchbauer G, Jäger W, Jirovetz L, Meyer F, Dietrich H
Institut für Pharmazeutische Chemie, Universität Wien.
Pharmazie. 1992 Aug;47(8):620-2.
The aromatherapeutical use of commercial valerian root oil (Chinese origin) and of pure fragrance compounds--borneol, isoborneol, bornyl acetate (main constituent of the proved valerian root oil) and isobornyl acetate--as potentially drugs with sedative effects after inhalation was investigated in an animal experiment (mice). In additional analyses the mice were treated i.p. by caffeine and distinct sedative effects were observed only by inhalation of the cited substances.