Derenne J P, Delclaux B
Service de Pneumologie, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Respiration. 1992;59 Suppl 3:28-31. doi: 10.1159/000196128.
The preventive effect of OM-85 BV on recurrent ENT and respiratory tract infections has been documented in a series of clinical trials. This article reviews the more significant controlled clinical trials investigating the efficacy and safety of OM-85 BV in airway infections. The literature reviewed covers all age groups. In summary, the administration of OM-85 BV was associated with a decrease in the number of acute exacerbations, with an increase in the number of patients remaining free from infections and with a decrease in antibiotic consumption. These results indicate the efficacy of oral immunostimulation with the bacterial extract OM-85 BV in all age groups and demonstrate its protective effect against recurrent airway infections.
一系列临床试验已证明OM-85 BV对耳鼻喉及呼吸道反复感染具有预防作用。本文回顾了调查OM-85 BV在气道感染中疗效和安全性的更重要的对照临床试验。所回顾的文献涵盖了所有年龄组。总之，服用OM-85 BV与急性加重次数减少、无感染患者数量增加以及抗生素消耗量减少相关。这些结果表明，使用细菌提取物OM-85 BV进行口服免疫刺激在所有年龄组均有效，并证明了其对反复气道感染的保护作用。
