Talbot S, Kilpatrick D, Jonathan A, Raphael M J
Br Heart J. 1977 Oct;39(10):1109-13. doi: 10.1136/hrt.39.10.1109.
Left ventricular volumes were estimated in 59 patients, who were investigated by single plane ventriculography and coronary arteriography. The relation of the left ventricular end-diastolic volumes to the QRS voltage of the 12-lead electrocardiograms and Frank vectorcardiograms was examined. It was found that the maximum spatial QRS voltage and the R wave voltage of leads V5 and V6 in patients without left ventricular hypertrophy were inversely correlated with end-diastolic volume. This inverse relation of QRS voltage and left ventricular volume may explain loss of QRS voltage with dilatation of the heart. In patients with left ventricular hypertropy QRS voltage is usually positively correlated with the degree of hypertrophy, but there is no significant correlation in the presence of cardiac dilatation. If the results of this study are extrapolated to patients with left ventricular hypertrophy and cardiac dilatation, then the inverse correlation of volume and QRS voltage may reduce the diagnostic sensitivity of unipolar chest lead and vectorcardiographic criteria of left ventricular hypertrophy.
对59例患者进行了左心室容积评估，这些患者接受了单平面心室造影和冠状动脉造影检查。研究了左心室舒张末期容积与12导联心电图和Frank向量心电图QRS电压之间的关系。结果发现，无左心室肥厚患者的最大空间QRS电压以及V5和V6导联的R波电压与舒张末期容积呈负相关。QRS电压与左心室容积的这种负相关关系可能解释了心脏扩张时QRS电压的降低。在左心室肥厚患者中，QRS电压通常与肥厚程度呈正相关，但在存在心脏扩张时无显著相关性。如果将本研究结果外推至左心室肥厚和心脏扩张患者，那么容积与QRS电压的负相关可能会降低单极胸导联和左心室肥厚向量心电图标准的诊断敏感性。
