Ponton C W, Don M, Eggermont J J
Electrophysiology Laboratory, House Ear Institute, Los Angeles, California.
Scand Audiol. 1992;21(3):131-41. doi: 10.3109/01050399209045993.
The high-pass noise masking technique was used to obtain derived frequency-specific cochlear microphonics (CM) from subtracted waveforms to rarefaction and condensation stimuli recorded with a tympanic membrane electrode. Two characteristics suggest that the response is place-specific CM: the derived response retains the same frequency as the stimulating toneburst and the response follows the stimulus polarity. For click stimulation, derived neural responses make the place-specific CM difficult to observe except in the 2-1 kHz derived band. In contrast, place-specific CM evoked by 0.5 and 1 kHz tonebursts can usually be detected in at least three derived bands. The amplitude of the response is largest in the derived band with center-frequency (CF) just above that of the toneburst. This discovery of a place-specific CM offers the possibility of assessing (outer) hair cell function in the apical part of the human cochlea.
高通噪声掩蔽技术用于从用鼓膜电极记录的稀疏和压缩刺激的减法波形中获得特定频率的耳蜗微音电位（CM）。两个特征表明该反应是部位特异性CM：导出的反应保留与刺激短纯音相同的频率，并且反应跟随刺激极性。对于点击刺激，导出的神经反应使得部位特异性CM难以观察到，除了在2-1kHz导出频段。相比之下，由0.5kHz和1kHz短纯音诱发的部位特异性CM通常可以在至少三个导出频段中检测到。反应的幅度在中心频率（CF）略高于短纯音的导出频段中最大。这种部位特异性CM的发现为评估人类耳蜗顶部（外）毛细胞功能提供了可能性。
