[胆固醇油酸酯（-1-14C）注入清醒猫脑室后在脑组织中的分布、摄取及水解]

[Distribution, uptake and hydrolysis of cholesterol oleate (-1-14C) in brain tissue after its injection in the cerebral ventricles of the conscious cat].

作者信息

Stojanovic N, Katanic D, Samardzic R, Beleslin D

出版信息

C R Seances Soc Biol Fil. 1977;171(3):525-34.

Abstract

Distribution, uptake and hydrolysys of cholesteryl oleate (-1-14C) in vivo in the cat's brain were investigated. Four hours following intraventricular injection of cholesteryl oleate (-1-14C), about one third of the injected radioactivity was taken up and about 50 % of that radioactive material was hydrolysed by brain tissue. Even more, the labelled material was found in the brain tissue surrounding the cerebral ventricles as well as in the cerebral cortex, but in varying amounts: the smallest amounts were found in the cerebral cortex, while the highest were in the hypothalamus. Radioactive material was also detected in the peripheral venous blood.

摘要

研究了油酸胆甾醇酯（-1-¹⁴C）在猫脑内的体内分布、摄取和水解情况。脑室内注射油酸胆甾醇酯（-1-¹⁴C）4小时后，约三分之一的注入放射性被摄取，且约50%的放射性物质被脑组织水解。此外，在脑室周围的脑组织以及大脑皮层中均发现了标记物质，但含量不同：大脑皮层中的含量最少，而下丘脑中的含量最高。在外周静脉血中也检测到了放射性物质。

相似文献

1

[Distribution, uptake and hydrolysis of cholesterol oleate (-1-14C) in brain tissue after its injection in the cerebral ventricles of the conscious cat].[胆固醇油酸酯（-1-14C）注入清醒猫脑室后在脑组织中的分布、摄取及水解]

C R Seances Soc Biol Fil. 1977;171(3):525-34.

2

[Metabolism of (1-14C) cholesteryl oleate in the brain of the cat].[猫脑中（1-14C）胆固醇油酸酯的代谢]

C R Seances Soc Biol Fil. 1980;174(2):127-31.

3

[Distribution of 1-14C palmitic acid in brain tissue after intraventricular injection in the conscious cat].[清醒猫脑室内注射1-14C棕榈酸后在脑组织中的分布]

C R Seances Soc Biol Fil. 1978;172(1):79-83.

4

[Uptake and esterification of (4-14C) cholesterol after injection into the cerebral ventricles of conscious cats].[向清醒猫脑室内注射（4-¹⁴C）胆固醇后的摄取与酯化]

C R Seances Soc Biol Fil. 1979;173(1):47-50.

5

[Metabolism of (1-14C)-palmitic acid in the cat's brain].[猫脑中（1-14C）-棕榈酸的代谢]

C R Seances Soc Biol Fil. 1978;172(2):269-73.

6

Cholesteryl esters from oxidized low-density lipoproteins are in vivo rapidly hydrolyzed in rat Kupffer cells and transported to liver parenchymal cells and bile.来自氧化低密度脂蛋白的胆固醇酯在大鼠枯否细胞中于体内迅速水解，并转运至肝实质细胞和胆汁中。

Hepatology. 1994 Jun;19(6):1459-67.

7

Distribution of [4-14C]cholesterol in the brain tissue after its intraventricular injection into conscious cats.将[4-14C]胆固醇经脑室注射到清醒猫体内后，其在脑组织中的分布情况。

J Neurochem. 1975 Apr;24(4):837-8.

8

Selective uptake of high-density lipoprotein-associated cholesteryl esters by human hepatocytes in primary culture.原代培养的人肝细胞对高密度脂蛋白相关胆固醇酯的选择性摄取。

Hepatology. 1994 May;19(5):1100-14.

9

Accumulation of oleate-rich cholesteryl esters by acetyl-LDL in macrophages in the presence of an acyl-CoA: cholesterol acyltransferase inhibitor (Sandoz 58-035).在存在酰基辅酶A：胆固醇酰基转移酶抑制剂（山道士58 - 035）的情况下，巨噬细胞中富含油酸的胆固醇酯被乙酰低密度脂蛋白蓄积。

Biochem Int. 1990;20(2):389-96.

10

The study of nonspecific internalization of cholesteryl esters by the Hep G2 hepatoma cells.Hep G2肝癌细胞对胆固醇酯非特异性内化作用的研究。

Membr Cell Biol. 2000;14(2):205-17.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。