Lebedev O E, Sergeenko N G, Sal'nikov K V, Barskiĭ I Ia
Tsitologiia. 1992;34(3):39-45.
Comparative investigation of different mitochondrial oxidative metabolism inhibitors action on NAD(P)H and flavoproteins fluorescence intensity of minimal transformed 3T3 NIH mouse fibroblasts and rat HTC hepatoma cells was made. Principle differences were shown between these cells in oxidized flavoproteins fluorescence intensity changes under the action of used inhibitors. It is suggested that the unusual HTC hepatoma cells flavin fluorescence intensity increase is connected with the oxidation of unidentified flavin-containing component functionally attached to mitochondrial respiratory chain.
对不同线粒体氧化代谢抑制剂作用于最小转化的3T3 NIH小鼠成纤维细胞和大鼠HTC肝癌细胞的NAD(P)H和黄素蛋白荧光强度进行了比较研究。结果表明，在所使用的抑制剂作用下，这些细胞在氧化型黄素蛋白荧光强度变化方面存在主要差异。有人提出，HTC肝癌细胞黄素荧光强度异常增加与功能上附着于线粒体呼吸链的未鉴定含黄素成分的氧化有关。
