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一名成年患者葡萄球菌烫伤样皮肤综合征中的异常中性粒细胞趋化性和T淋巴细胞功能。

Abnormal neutrophil chemotaxis and T-lymphocyte function in staphylococcal scalded skin syndrome in an adult patient.

作者信息

Peterson P K, Laverdiere M, Quie P G, Sabath L D

出版信息

Infection. 1977;5(3):128-31. doi: 10.1007/BF01639745.

DOI:10.1007/BF01639745
PMID:144093
Abstract

Staphylococcal scalded skin syndrome, a disease rarely reported in adults, developed in a 38-year-old male while on steroid therapy for chronic active hepatitis. Studies of immunologic parameters important in staphylococcal host defense revealed normal opsonic activity and phagocytic function but marked defects in neutrophil chemotaxis and T-lymphocyte function. Compromised host defense appears to play a significant role in the pathogenesis of the syndrome in adults.

摘要

葡萄球菌烫伤样皮肤综合征在成人中鲜有报道,一名38岁男性在接受慢性活动性肝炎类固醇治疗时患上了该疾病。对葡萄球菌宿主防御中重要的免疫参数研究显示,其调理活性和吞噬功能正常,但中性粒细胞趋化性和T淋巴细胞功能存在明显缺陷。宿主防御受损似乎在成人该综合征的发病机制中起重要作用。

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引用本文的文献

1
Staphylococcal scalded skin syndrome in an immunocompromised adult.免疫功能低下成人的葡萄球菌性烫伤样皮肤综合征
Eur J Clin Microbiol Infect Dis. 1996 Jun;15(6):499-503. doi: 10.1007/BF01691318.

本文引用的文献

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A review of toxic epidermal necrolysis in Britain.英国中毒性表皮坏死松解症综述。
Br J Dermatol. 1967 Dec;79(12):662-71. doi: 10.1111/j.1365-2133.1967.tb11434.x.
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Resistance against Staphylococcus aureus.对金黄色葡萄球菌的耐药性。
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Experimental staphylococcal toxic epidermal necrolysis (TEN) in adult humans and mice.成人及小鼠的实验性葡萄球菌性中毒性表皮坏死松解症(TEN)
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Staphylococcal scalded skin syndrome: potentiation by immunosuppression in mice; toxin-mediated exfoliation in a healthy adult.葡萄球菌烫伤样皮肤综合征:小鼠免疫抑制的增强作用;健康成年人中的毒素介导的表皮剥脱
Infect Immun. 1974 Apr;9(4):636-40. doi: 10.1128/iai.9.4.636-640.1974.
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Staphylococcal scalded skin syndrome. Adult onset in a patient with deficient cell-mediated immunity.葡萄球菌性烫伤样皮肤综合征。细胞介导免疫缺陷患者的成人发病。
Arch Dermatol. 1974 Feb;109(2):239-41. doi: 10.1001/archderm.109.2.239.
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Letter: Staphylococcal scalded-skin syndrome in adults.信函:成人葡萄球菌性烫伤样皮肤综合征
N Engl J Med. 1974 Mar 7;290(10):577. doi: 10.1056/NEJM197403072901029.
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Staphylococcal scalded skin syndrome in an adult.成人葡萄球菌性烫伤样皮肤综合征
Arch Dermatol. 1973 Sep;108(3):408-10.
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Scalded-skin syndrome in adults.成人烫伤样皮肤综合征
N Engl J Med. 1973 May 24;288(21):1130. doi: 10.1056/NEJM197305242882123.
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Staphylococcal scalded-skin syndrome in an adult.成人葡萄球菌烫伤样皮肤综合征
N Engl J Med. 1972 Dec 28;287(26):1339-40. doi: 10.1056/NEJM197212282872608.
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Alternate-day prednisone. Leukocyte kinetics and susceptibility to infections.隔日服用泼尼松。白细胞动力学与感染易感性。
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