一名患有复发性细菌感染和湿疹的儿童中性粒细胞趋化性缺陷及血清IgE水平升高。左旋咪唑的影响。
Defective neutrophil chemotaxis and raised serum ige levels in a child with recurrent bacterial infections and eczema. Influence of levamisole.
作者信息
De Cree J, Emmery L, Timmermans J, Eeckels R, De Cock W, Verhaegen H
出版信息
Arch Dis Child. 1978 Feb;53(2):144-9. doi: 10.1136/adc.53.2.144.
Abstract
A 5 1/2-year-old girl, with a life-long history of recurrent staphylococcal infections and eczematous dermatitis had a defect in polymorphonuclear leucocyte chemotaxis and phagocytosis in autologous serum, a high serum IgE level, and a disturbed T cell function. Levamisole improved all the immunological abnormalities and there was a dramatic clinical improvement. Discontinuation of therapy with levamisole resulted in gradual deterioration.
摘要
一名5岁半女童，有复发性葡萄球菌感染和湿疹性皮炎的终生病史，其多形核白细胞趋化性和自体血清中的吞噬作用存在缺陷，血清IgE水平高，T细胞功能紊乱。左旋咪唑改善了所有免疫异常，临床症状显著改善。停用左旋咪唑治疗后病情逐渐恶化。
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