KIRTLAND H B, BROWN R G, MCDONALD R T
Calif Med. 1960 Jun;92(6):409-12.
Venous stasis, injury or alteration of the intima and alterations in the coagulability of the blood are the three most common etiologic factors in thrombophlebitis. Usually at least two of these factors must be present before the clinical manifestations of the disease develop.A plan of treatment based on correcting these three factors has been used in over 250 cases of thrombophlebitis, and it is believed that a significant decrease was brought about in the acute and long term disability and in the occurrence of complications. The program consists of absolute bed rest in a hospital for about a week, elevation of the foot of the bed, administration of anticoagulants and adenosine-5-monophosphate for at least six weeks, progressive ambulation after the fourth day of treatment, with avoidance of prolonged standing and sitting, and adequate elastic support. Treatment must be continued until the patient has returned to full, normal activity and all signs of phlebitis have disappeared.
静脉淤滞、内膜损伤或改变以及血液凝固性改变是血栓性静脉炎最常见的三个病因。通常在这些因素中至少有两个存在时，疾病的临床表现才会出现。基于纠正这三个因素的治疗方案已应用于250多例血栓性静脉炎患者，据信急性和长期残疾以及并发症的发生率都有显著降低。该方案包括在医院绝对卧床休息约一周，抬高床脚，至少六周给予抗凝剂和5'-单磷酸腺苷，治疗第四天后逐渐下床活动，避免长时间站立和坐着，以及给予足够的弹性支撑。治疗必须持续到患者恢复完全正常活动且静脉炎的所有体征消失。
