Zaragoza M R, Grossman H B
Department of Surgery, University of Michigan, Ann Arbor.
Urology. 1992 Nov;40(5):405-8. doi: 10.1016/0090-4295(92)90452-3.
A ten-year review of 198 patients with Stage D2 prostate cancer identified 13 patients (6.6%) who exhibited objective responses to hormonal treatment, as indicated by regression of a positive bone scan, CT scan, or chest x-ray film. Four patients had complete responses and 9 patients achieved partial responses as judged by the National Prostatic Cancer Project criteria. Median survival for those with objective treatment response has not yet been reached (> 44 months) compared with twenty-four months for the nonresponders (p = 0.00006). Although relatively uncommon, objective treatment response in Stage D2 prostate cancer is correlated with an improved prognosis.
一项对198例D2期前列腺癌患者的十年回顾研究发现，有13例患者（6.6%）对激素治疗表现出客观反应，表现为阳性骨扫描、CT扫描或胸部X光片的影像消退。根据国家前列腺癌项目标准判断，4例患者完全缓解，9例患者部分缓解。有客观治疗反应患者的中位生存期尚未达到（>44个月），而无反应者为24个月（p = 0.00006）。虽然相对不常见，但D2期前列腺癌的客观治疗反应与预后改善相关。
