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睾丸微结石症的发病率。

Incidence of testicular microlithiasis.

作者信息

Höbarth K, Susani M, Szabo N, Kratzik C

机构信息

Department of Urology, University of Vienna Medical School, Austria.

出版信息

Urology. 1992 Nov;40(5):464-7. doi: 10.1016/0090-4295(92)90467-b.

DOI:10.1016/0090-4295(92)90467-b
PMID:1441049
Abstract

In adults polytopic intratubular calcifications of the testes are rare. Known as testicular microlithiasis, they manifest themselves in a characteristic echo pattern on sonography with high-frequency transducers (5 to 10 MHz). This consists of multiple echogenic specks in an otherwise normal testicular parenchyma. In a retrospective analysis of 1,710 testicular sonograms of adults, bilateral intratesticular microliths were found in 11 cases (0.6%). In 5 of them, the microliths were associated with a testicular tumor. One patient with a tumor in the contralateral testis had undergone radiotherapy and another one presented with hypogonadism. Four patients with noncontributory histories presented with varicocele or epididymal cyst. Sonographic findings were confirmed histologically in 6 patients. Multiple intratubular calcifications were found in all of them. The pathogenesis of testicular microliths is still poorly understood. Their clinical relevance is unclear, but their incidence in adults appears to be higher than reported in the literature.

摘要

在成年人中,睾丸多发性管内钙化很少见。它们被称为睾丸微石症,在使用高频换能器(5至10兆赫)进行超声检查时,会呈现出特征性的回声模式。这表现为在原本正常的睾丸实质内有多个强回声斑点。在一项对1710例成年男性睾丸超声图的回顾性分析中,发现11例(0.6%)存在双侧睾丸微石症。其中5例微石症与睾丸肿瘤有关。1例对侧睾丸有肿瘤的患者曾接受过放疗,另1例伴有性腺功能减退。4例无相关病史的患者表现为精索静脉曲张或附睾囊肿。6例患者的超声检查结果经组织学证实。在所有这些患者中均发现了多发性管内钙化。睾丸微石症的发病机制仍知之甚少。它们的临床相关性尚不清楚,但在成年人中的发病率似乎高于文献报道。

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1
Incidence of testicular microlithiasis.睾丸微结石症的发病率。
Urology. 1992 Nov;40(5):464-7. doi: 10.1016/0090-4295(92)90467-b.
2
Sonographic appearance of testicular microlithiasis.睾丸微结石症的超声表现。
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Testicular microlithiasis: association with male infertility.睾丸微石症:与男性不育的关联
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Testicular microlithiasis: sonographic and clinical features.睾丸微结石症:超声及临床特征
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Testicular calcifications: incidence, histology and proposed pathological criteria for testicular microlithiasis.
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引用本文的文献

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Clinical and imaging diagnosis of pediatric testicular microlithiasis: a physician's dilemma.小儿睾丸微结石症的临床与影像学诊断:医生的两难困境
Front Pediatr. 2025 Jul 30;13:1554081. doi: 10.3389/fped.2025.1554081. eCollection 2025.
2
Testicular Cancer in Infertile Men With and Without Testicular Microlithiasis: A Systematic Review and Meta-Analysis of Case-Control Studies.患有和未患有睾丸微结石症的不育男性的睾丸癌:病例对照研究的系统评价和荟萃分析
Front Endocrinol (Lausanne). 2019 Mar 21;10:164. doi: 10.3389/fendo.2019.00164. eCollection 2019.
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Evaluation of testicular microlithiasis in varicoceles.
精索静脉曲张中睾丸微结石症的评估
Reprod Med Biol. 2002 Dec 11;1(2):75-79. doi: 10.1046/j.1445-5781.2002.00013.x. eCollection 2002 Sep.
4
Changes of calcific density in pediatric patients with testicular microlithiasis.小儿睾丸微石症患者钙化密度的变化
Korean J Urol. 2015 Apr;56(4):318-23. doi: 10.4111/kju.2015.56.4.318. Epub 2015 Apr 3.
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Testicular microlithiasis: is there a need for surveillance in the absence of other risk factors?睾丸微石症:在没有其他危险因素的情况下是否需要进行监测?
Eur Radiol. 2012 Nov;22(11):2540-6. doi: 10.1007/s00330-012-2520-4. Epub 2012 Jun 19.
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Testicular adrenal rest tumors in patients with congenital adrenal hyperplasia.先天性肾上腺皮质增生症患者的睾丸肾上腺残余瘤
J Clin Res Pediatr Endocrinol. 2012 Jun;4(2):94-100. doi: 10.4274/jcrpe.563.
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Testicular microlithiasis: prevalence and clinical significance in a population referred for scrotal ultrasonography.睾丸微结石症:阴囊超声检查人群中的患病率及临床意义
Korean J Urol. 2011 Mar;52(3):172-7. doi: 10.4111/kju.2011.52.3.172. Epub 2011 Mar 18.
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Testicular microlithiasis: Is there an agreed protocol?睾丸微结石症:是否存在商定的方案?
Indian J Urol. 2007 Jul;23(3):234-9. doi: 10.4103/0970-1591.33442.
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Testicular microlithiasis: another starry sky appearance.睾丸微结石症:另一种星空样表现。
Clin Med Res. 2007 Oct;5(3):163-4. doi: 10.3121/cmr.2007.760.
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Int Urol Nephrol. 2007;39(4):1177-81. doi: 10.1007/s11255-007-9203-0. Epub 2007 Jun 30.