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[奥地利的四年美沙酮替代疗法]

[4 years' methadone substitution therapy in Austria].

作者信息

Loimer N

机构信息

Allgemeines Krankenhaus der Stadt Wien, Psychiatrische Universitätsklinik.

出版信息

Wien Klin Wochenschr. 1992;104(19):583-8.

PMID:1441552
Abstract

On September 25th 1987 methadone was legalized for therapeutic use in Austria. During the past four years altogether 1828 opiate addicts were admitted to methadone maintenance treatment. 439 females and 926 males were currently being treated in December 1991; their age ranged from 16-59 years, the daily oral d,l methadone dose levels varied between 10 mg and 250 mg per day. Only 406 doctors and 123 pharmacies participate in methadone maintenance treatment, which does not provide complete cover for the area in spite of increased finding. Moreover, the doctors' skills in this treatment have to be improved by requisite training. As Austrian experience shows, methadone treatment offers a first step towards social rehabilitation for drug addicts who have been living as criminals on the fringe of society. Socioeconomic data, as well as criminal behaviour changed dramatically for the better due to this treatment in Austria. Physicians have a clear responsibility to lead the effort on all fronts in the implementation of this treatment modality. Therapeutic drug monitoring should become routine in methadone treatment to ensure compliance and to achieve optimum results, especially in patients who complain of withdrawal symptoms and continue high-risk behaviour and to increase acceptance of substitution therapy. The Austrian treatment model for methadone maintenance treatment is a positive example for other countries who wish to introduce this treatment modality for drug addiction.

摘要

1987年9月25日,美沙酮在奥地利被合法化用于治疗用途。在过去四年中,共有1828名阿片类药物成瘾者接受了美沙酮维持治疗。1991年12月,有439名女性和926名男性正在接受治疗;他们的年龄在16至59岁之间,每日口服消旋美沙酮剂量水平在每天10毫克至250毫克之间。只有406名医生和123家药店参与美沙酮维持治疗,尽管资金有所增加,但仍无法完全覆盖该地区。此外,医生在这种治疗方面的技能必须通过必要的培训加以提高。正如奥地利的经验所示,美沙酮治疗为那些一直作为犯罪分子生活在社会边缘的吸毒者提供了迈向社会康复的第一步。在奥地利,由于这种治疗,社会经济数据以及犯罪行为都有了显著改善。医生有明确的责任在实施这种治疗方式的所有方面发挥带头作用。治疗药物监测应成为美沙酮治疗的常规手段,以确保依从性并取得最佳效果,特别是对于那些抱怨有戒断症状并继续有高风险行为的患者,并提高替代疗法的接受度。奥地利的美沙酮维持治疗模式为其他希望引入这种药物成瘾治疗方式的国家树立了一个积极的榜样。

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