Midtbø M, Halse A
Department of Orthodontics and Facial Orthopedics, School of Dentistry, University of Bergen, Norway.
Acta Odontol Scand. 1992 Oct;50(5):303-12. doi: 10.3109/00016359209012777.
A major problem for patients with Turner syndrome is their small body height. The rapid biotechnologic development has now made treatment with growth hormone possible at a larger scale. The aim of this investigation was to evaluate skeletal maturity, dental maturity, and eruption in a group of young patients before hormone therapy. The material comprised 33 patients aged 7-16.7 years. The skeletal maturity, as judged from hand radiographs, was on an average 2.3 years retarded (p < 0.001) and showed increasing retardation with increasing age. The dental maturity, assessed from the formation stages of the permanent teeth on panoramic radiographs, was accelerated, with a mean value of 1 year (p < 0.001). The timing of clinical eruption did not differ significantly from that of our reference material; the Turner girls were on an average 3.7 months ahead. Several patients had local eruption problems, especially in the maxillary lateral segments. It is suggested that disharmony between tooth size and arch size may contribute to this problem.
特纳综合征患者面临的一个主要问题是身材矮小。生物技术的快速发展现已使大规模使用生长激素治疗成为可能。本研究的目的是评估一组年轻患者在激素治疗前的骨骼成熟度、牙齿成熟度和萌出情况。研究材料包括33名年龄在7至16.7岁之间的患者。根据手部X光片判断,骨骼成熟度平均延迟2.3年(p < 0.001),且随着年龄增长延迟程度增加。根据全景X光片上恒牙的形成阶段评估,牙齿成熟度提前,平均值为1年(p < 0.001)。临床萌出时间与我们的参考材料相比无显著差异;特纳综合征女孩平均提前3.7个月。部分患者存在局部萌出问题,尤其是上颌侧切牙区域。有人认为牙齿大小与牙弓大小不匹配可能是导致该问题的原因。