Vermorken A J, Groeneveld A A, Hilderink J M, DeWaal R, Bloemendal H
Mol Biol Rep. 1977 Sep;3(5):371-8. doi: 10.1007/BF00420396.
Lens epithelial cells can be kept in their original differentiated state or brought to dedifferentiation depending on the culture conditions. The different stages of differentiation can be identified using specific markers, namely the activity of steroid metabolizing enzymes, and the synthesis of specific structural lens polypeptides. For this reason lens epithelial cells in tissue culture provide a unique system for the study of the regulation of RNA and protein biosynthesis.
晶状体上皮细胞可根据培养条件保持其原始分化状态或发生去分化。利用特定标志物，即类固醇代谢酶的活性和特定晶状体结构多肽的合成，可识别分化的不同阶段。因此，组织培养中的晶状体上皮细胞为研究RNA和蛋白质生物合成的调控提供了一个独特的系统。
