Cristofori P, Terron A, Marella M, Moretti U, Pasqualicchio M, Velo G P, Milanino R
Laboratorio di Patologia, Università degli Studi, Verona, Italia.
Agents Actions. 1992;Spec No:C118-20.
Complete toxicological examinations in female rats fed an "anti-inflammatory" 200 ppm copper-containing diet for 30 and 58 days were performed. Copper was found to accumulate in liver, kidneys and paws; however, at the hematological, clinical chemical and histopathological levels, this treatment did not seem able to induce any toxic accumulation phenomenon in the examined rats.
对喂食含200 ppm铜的“抗炎”饮食30天和58天的雌性大鼠进行了全面的毒理学检查。发现铜在肝脏、肾脏和爪子中蓄积;然而,在血液学、临床化学和组织病理学水平上,这种处理似乎未能在受试大鼠中诱导任何毒性蓄积现象。