Tachinami K, Katayama T, Takeda N, Hayami H, Kubota Y, Okada E
Department of Ophthalmology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.
Nippon Ganka Gakkai Zasshi. 1992 Oct;96(10):1336-40.
The authors report a case of metastatic carcinoma to the retina. The patient was a 61-year-old man who had an operation for a well-differentiated adenocarcinoma of the rectum. Ophthalmoscopic examination disclosed a single, white, elevated mass lesion surrounded by serous retinal detachment located in the upper part of the macula of the right eye. A few retinal hemorrhages existed around the lesion. Fluorescein angiography revealed partially obscured retinal vessels due to compression by the tumor and arteriovenous anastomosis. Postmortem pathologic examination confirmed metastases to the brain, lung and retina. Microscopic examination showed a retinal lesion and tumor cells in the right eye. Tumor cells, similar to the carcinoma of the rectum, were present only in the neurosensory retina and did not invade the pigmented epithelium or choroid.
作者报告了一例视网膜转移性癌病例。患者为一名61岁男性，曾因高分化直肠腺癌接受手术。眼底检查发现右眼黄斑上方有一个单一的白色隆起性肿块病变，周围伴有浆液性视网膜脱离。病变周围有少量视网膜出血。荧光素血管造影显示肿瘤压迫导致视网膜血管部分模糊以及动静脉吻合。尸检病理检查证实脑、肺和视网膜有转移。显微镜检查显示右眼有视网膜病变及肿瘤细胞。肿瘤细胞与直肠癌细胞相似，仅存在于神经感觉视网膜，未侵犯色素上皮或脉络膜。
