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骶前神经切除术治疗子宫内膜异位症相关盆腔疼痛:一项对照研究。

Presacral neurectomy for the treatment of pelvic pain associated with endometriosis: a controlled study.

作者信息

Candiani G B, Fedele L, Vercellini P, Bianchi S, Di Nola G

机构信息

Department of Obstetrics and Gynecology, University of Milan, Italy.

出版信息

Am J Obstet Gynecol. 1992 Jul;167(1):100-3. doi: 10.1016/s0002-9378(11)91636-6.

Abstract

OBJECTIVE

Our objective was to evaluate the efficacy of presacral neurectomy combined with conservative surgery for the treatment of pelvic pain associated with endometriosis.

STUDY DESIGN

In a randomized, controlled study performed in a tertiary institution 71 patients with moderate or severe endometriosis and midline dysmenorrhea were randomly assigned to conservative surgery alone (n = 36) or conservative surgery and presacral neurectomy (n = 35). Main outcome measures were relief of dysmenorrhea, pelvic pain, and deep dyspareunia after surgery according to a multidimensional and an analog pain scale.

RESULTS

Presacral neurectomy markedly reduced the midline component of menstrual pain, but no statistically significant differences were observed between the two groups in the frequency and severity of dysmenorrhea, pelvic pain, and dyspareunia in the long-term follow-up. After presacral neurectomy, constipation developed or worsened in 13 patients and urinary urgency occurred in three and a painless first stage of labor in two.

CONCLUSION

Presacral neurectomy should be combined with conservative surgery for endometriosis only in selected cases.

摘要

目的

我们的目的是评估骶前神经切除术联合保守手术治疗子宫内膜异位症相关盆腔疼痛的疗效。

研究设计

在一家三级医疗机构进行的一项随机对照研究中,71例中度或重度子宫内膜异位症伴中线痛经患者被随机分为单纯保守手术组(n = 36)或保守手术加骶前神经切除术组(n = 35)。主要结局指标是根据多维和模拟疼痛量表评估术后痛经、盆腔疼痛及深部性交困难的缓解情况。

结果

骶前神经切除术显著减轻了经期疼痛的中线部分,但在长期随访中,两组在痛经、盆腔疼痛及性交困难的频率和严重程度方面未观察到统计学上的显著差异。骶前神经切除术后,13例患者出现便秘或便秘加重,3例出现尿急,2例出现无痛第一产程。

结论

骶前神经切除术仅在特定病例中应与子宫内膜异位症的保守手术联合应用。

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