子宫内膜异位症早期黄素化未破裂卵泡作为不明原因不孕症的一个病因

Luteinized unruptured follicle in the early stages of endometriosis as a cause of unexplained infertility.

作者信息

Mio Y, Toda T, Harada T, Terakawa N

机构信息

Department of Obstetrics and Gynecology, Tottori University School of Medicine, Yonago, Japan.

出版信息

Am J Obstet Gynecol. 1992 Jul;167(1):271-3. doi: 10.1016/s0002-9378(11)91673-1.

DOI:10.1016/s0002-9378(11)91673-1

PMID:1442941

Abstract

OBJECTIVE

We attempted to clarify the relationship between luteinized unruptured follicle, which occurs in the early stages of endometriosis, and unexplained infertility.

STUDY DESIGN

Seventy patients who had unexplained infertility were reviewed.

RESULTS

Laparoscopic examination showed that 47 patients (67%) had endometriosis; of these, 40 (85%) had minimal or mild disease. The incidence of luteinized unruptured follicle was higher (p < 0.05) in patients who had endometriosis (35%/patient and 25%/cycle) compared with patients who did not have endometriosis (11%/patient and 7%/cycle). Degenerated oocyte cumuli were collected in 6 (43%) of 14 luteinized unruptured follicles diagnosed by transvaginal ultrasound.

CONCLUSIONS

These results show that luteinized unruptured follicle is common in patients who have mild or minimal endometriosis and that it may be one of the causes of endometriosis-associated infertility. Transvaginal ultrasound-guided follicular puncture of luteinized unruptured follicle during the mid luteal phase may be useful in establishing a definitive diagnosis of luteinized unruptured follicle.

摘要

目的

我们试图阐明子宫内膜异位症早期出现的黄素化未破裂卵泡与不明原因不孕症之间的关系。

研究设计

对70例不明原因不孕症患者进行了回顾性研究。

结果

腹腔镜检查显示，47例（67%）患者患有子宫内膜异位症；其中，40例（85%）为轻度或中度疾病。与未患子宫内膜异位症的患者（11%/患者和7%/周期）相比，患子宫内膜异位症的患者黄素化未破裂卵泡的发生率更高（p < 0.05）（35%/患者和25%/周期）。经阴道超声诊断的14个黄素化未破裂卵泡中有6个（43%）收集到了退化的卵丘。