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选择性支气管内空气注入治疗急性肺叶不张的疗效

Efficacy of selective intrabronchial air insufflation in acute lobar collapse.

作者信息

Haenel J B, Moore F A, Moore E E, Read R A

机构信息

Department of Surgery, Denver General Hospital, University of Colorado Health Science Center 80204-4507.

出版信息

Am J Surg. 1992 Nov;164(5):501-5. doi: 10.1016/s0002-9610(05)81189-4.

Abstract

Flexible fiberoptic bronchoscopy (FFB) to remove mucous plugs followed by selective intrabronchial air insufflation (SII) to expand the atelectatic lung was used in 17 surgical intensive care unit (SICU) patients with pulmonary lobar collapse. Thirteen patients were admitted for acute trauma, and the remainder were elderly postoperative patients. Lobar collapses occurred on SICU days 1 to 18 (mean +/- SEM: 5 +/- 1 days), and duration ranged from 4 to 258 hours (mean: 77 +/- 18 hours). Indications for FFB with SII included critical hypoxemia in 5 patients, worsening collapse in 2, and failure to respond to aggressive respiratory care in 10 (59%). FFB with SII was effective in 14 (82%) patients: 10 achieved full lung re-expansion, and 4 partial lung re-expansion. When lobar collapse was of less than 72 hours' duration, 92% (12 of 13) of patients had lungs re-expanded compared with 50% (2 of 4) whose collapse existed for more than 72 hours. The mean PaO2/FIO2 (fraction inspired oxygen) ratio was 135 +/- 18 prior to FFB with SII and increased to 205 +/- 21 after FFB with SII. Complications were minor and clinically insignificant. In conclusion, SII appears to be a simple, safe, effective adjunct to FFB in the treatment of SICU patients with pulmonary lobar collapse.

摘要

17例入住外科重症监护病房(SICU)且出现肺叶萎陷的患者接受了如下治疗:首先通过可弯曲纤维支气管镜(FFB)清除黏液栓,随后进行选择性支气管内充气(SII)以扩张萎陷肺组织。13例患者因急性创伤入院,其余为老年术后患者。肺叶萎陷发生在入住SICU的第1至18天(平均±标准误:5±1天),持续时间为4至258小时(平均:77±18小时)。FFB联合SII的适应证包括5例患者存在严重低氧血症、2例患者肺萎陷加重以及10例患者(59%)对积极的呼吸治疗无反应。FFB联合SII治疗对14例(82%)患者有效:10例患者肺完全复张,4例患者部分肺复张。当肺叶萎陷持续时间小于72小时时,92%(13例中的12例)的患者肺复张,而萎陷持续时间超过72小时的患者中这一比例为50%(4例中的2例)。在进行FFB联合SII治疗前,平均动脉血氧分压/吸入氧分数(PaO2/FIO2)比值为135±18,治疗后升至205±21。并发症轻微,临床意义不大。总之,在治疗入住SICU且出现肺叶萎陷的患者时,SII似乎是一种简单、安全、有效的FFB辅助治疗方法。

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