Debord P, Postaire M, Pham-Huy C, Hamon M
Laboratoire de pharmacie et toxicologie, hôpital Necker-Enfants Malades, Paris, France.
Ann Biol Clin (Paris). 1992;50(2):77-80.
Gas capillary chromatography (GCC) determination of mannitol and lactulose in urine after oral intake is a method for assessing the intestinal permeability in various bowel diseases. The method proposed, using gas capillary chromatography with flame ionization detection after silylation of urine residue, gives good results: coefficients of variation varied from 6 to 8.7% for mannitol and 7.5 to 13.7% for lactulose. Detection limit was 5 mg/l for both compounds.
口服后采用气相毛细管色谱法（GCC）测定尿液中的甘露醇和乳果糖是一种评估各种肠道疾病中肠道通透性的方法。所提出的方法是在尿液残渣硅烷化后，使用带有火焰离子化检测的气相毛细管色谱法，结果良好：甘露醇的变异系数在6%至8.7%之间，乳果糖的变异系数在7.5%至13.7%之间。两种化合物的检测限均为5 mg/l。
