SAHA A, GHOSH J
Science. 1960 Aug 19;132(3425):468-70. doi: 10.1126/science.132.3425.468.
In vivo studies of the biosynthesis of chick hemoglobins 1 and 2 showed an over-all higher incorporation of glycine-2-C(14), valine-4-C(14), valine-1-C(14), leucine-G-C(14), and histidine-(2-ring)-C(14) in hemoglobin 2; in vitro studies made with intact nucleated chick erythrocytes showed the higher incorporation of glycine-2-C(14), valine-1-C(14), and histidine-(2-ring)-C(14) in hemoglobin 1. Hybridization of chick hemoglobins produced an electrophoretically distinguishable new component.
对鸡血红蛋白1和2生物合成的体内研究表明，血红蛋白2中甘氨酸-2-C(14)、缬氨酸-4-C(14)、缬氨酸-1-C(14)、亮氨酸-G-C(14)和组氨酸-(2-环)-C(14)的总体掺入量更高；用完整的有核鸡红细胞进行的体外研究表明，血红蛋白1中甘氨酸-2-C(14)、缬氨酸-1-C(14)和组氨酸-(2-环)-C(14)的掺入量更高。鸡血红蛋白的杂交产生了一种电泳上可区分的新成分。
