Sartor F A, Rondia D J, Claeys F D, Staessen J A, Lauwerys R R, Bernard A M, Buchet J P, Roels H A, Bruaux P J, Ducoffre G M
Environmental Toxicology Unit, University of Liege, Belgium.
Arch Environ Health. 1992 Sep-Oct;47(5):347-53. doi: 10.1080/00039896.1992.9938373.
The body burden of cadmium, as estimated from 24-h urine cadmium levels, was determined in 1,523 subjects who were not occupationally exposed and who lived in five areas of Belgium. Urinary cadmium levels differed significantly with place of residence. These differences persisted after standardization for the other significant determinants (i.e., age, body mass index, smoking habits, social class, alcohol consumption, and menopause). The highest 24-h urine cadmium levels were found in subjects who lived in areas that contained cadmium-polluted soils. The body burden overload has been attributed mainly to the consumption of locally grown vegetables and the use of contaminated well water for cooking and drinking. Blood cadmium levels were also dependent on place of residence. However, the geographical differences in blood cadmium did not parallel those of urine cadmium. Blood cadmium is more influenced by recent exposure; therefore, this latter observation might reflect the recent implementation of preventive measures in some areas.
通过24小时尿镉水平估算的镉体内负荷，在1523名未接触职业镉且居住在比利时五个地区的受试者中进行了测定。尿镉水平因居住地不同而有显著差异。在对其他显著决定因素（即年龄、体重指数、吸烟习惯、社会阶层、饮酒量和绝经情况）进行标准化后，这些差异仍然存在。24小时尿镉水平最高的受试者居住在土壤镉污染地区。体内负荷超标主要归因于食用当地种植的蔬菜以及使用受污染的井水进行烹饪和饮用。血镉水平也取决于居住地。然而，血镉的地理差异与尿镉的差异并不平行。血镉受近期接触的影响更大；因此，后一观察结果可能反映了一些地区最近实施的预防措施。
