SIMMONS M W
Calif Med. 1960 Feb;92(2):155-8.
Intranasal injections into the inferior turbinates of a slightly form of prednisolone TBA (Hydeltra(R) TBA) into persons with complaint of nasal obstruction gave considerable relief in 78 per cent of cases. Nasal hyperfunction due to seasonal allergic rhinitis, vasomotor rhinitis and secondary nasal edema from sinusitis was the indication for use. No local or general reactions other than a small amount of bleeding at the time of injection was noted. This method allows full utilization of the anti-inflammatory activity of corticosteroids at the local tissue level without producing a systemic effect.
对有鼻塞症状的患者在下鼻甲进行稍低剂量的泼尼松龙TBA(Hydeltra® TBA)鼻内注射,78%的病例症状得到显著缓解。季节性过敏性鼻炎、血管运动性鼻炎以及鼻窦炎继发鼻水肿所致的鼻功能亢进是使用该方法的适应症。除注射时少量出血外,未观察到局部或全身反应。该方法可在局部组织水平充分发挥皮质类固醇的抗炎活性,而不产生全身效应。