Grzincich Gianluigi, Capra Lucetta, Cammarata Maria Grazia, Spaggiari Cinzia, Pisi Giovanna
Department of Pediatrics, University of Parma, Italy.
Acta Biomed. 2004 Apr;75(1):22-5.
Intranasal corticosteroids (IC) are most commonly prescribed to treat allergic rhinitis (perennial and seasonal). There are now many IC available to treat rhinitis, all effective on nasal obstruction, rhinorrhea, sneezing, itching and post-nasal drip. IC are superior to oral antihistamines for the relief of all nasal symptoms; however, antihistamines are first line therapy if allergic conjunctivitis coexists. At present the data do not support the use of IC in the management of otitis media with effusion (OME), nasal polyposis and sinusitis, but when topical IC are administered together with antibiotic therapy they facilitate a more rapid improvement of symptoms.
鼻内用皮质类固醇(IC)是治疗变应性鼻炎(常年性和季节性)最常用的药物。目前有多种IC可用于治疗鼻炎,对鼻塞、流涕、打喷嚏、瘙痒和鼻后滴漏均有效。IC在缓解所有鼻部症状方面优于口服抗组胺药;然而,如果同时存在变应性结膜炎,抗组胺药是一线治疗药物。目前的数据不支持将IC用于治疗分泌性中耳炎(OME)、鼻息肉和鼻窦炎,但局部使用IC与抗生素治疗联合应用时,可促进症状更快改善。