LaBarge E, Smith D S, Dick L, Storandt M
Department of Neurology and Neurological Surgery, Washington University School of Medicine, St Louis, MO 63110.
Arch Neurol. 1992 Nov;49(11):1151-6. doi: 10.1001/archneur.1992.00530350065021.
This study describes graphic errors made in writing a simple sentence in 368 healthy older adults and individuals in different stages of dementia of the Alzheimer type. Errors of agraphia were present in both healthy and demented people and, in general, increased with the severity of dementia. The errors of agraphia were not correlated with measures of aphasia or psychometric measures of language and motor performance. Writing skill may represent procedural memory, and agraphia errors indicate alterations in long-term memory in dementia of the Alzheimer type.
本研究描述了368名健康老年人以及处于不同阶段的阿尔茨海默病型痴呆患者在书写一个简单句子时出现的书写错误。失写症错误在健康人和痴呆患者中均有出现，总体上随着痴呆严重程度的增加而增多。失写症错误与失语症测量指标或语言及运动表现的心理测量指标无关。书写技能可能代表程序性记忆，而失写症错误表明阿尔茨海默病型痴呆患者的长期记忆出现了改变。
