Horner J, Heyman A, Dawson D, Rogers H
Department of Surgery, Duke University Medical Center, Durham, NC 27710.
Arch Neurol. 1988 Jul;45(7):760-3. doi: 10.1001/archneur.1988.00520310066019.
Impairment of writing ability was studied in 20 patients with mild to moderate dementia caused by early-onset Alzheimer's disease. A multicomponent analysis was made of a brief narrative writing sample obtained from each patient, and this writing proficiency score was compared with results of standard tests of cognitive function as well as ratings of the degree of dementia. In these patients, significant correlations were observed between this brief test of narrative writing ability and the severity of dementia. An analysis of writing proficiency appears to be a simple means of assessing the severity of dementia caused by Alzheimer's disease. Further studies are needed to show the potential usefulness of such measures of agraphia in subtyping this disease.
