Zarour H, Grob J J, Andrac L, Bonerandi J J
Service de Dermatologie, Hôpital Sainte-Marguerite, Marseille, France.
Dermatology. 1992;185(3):205-9. doi: 10.1159/000247448.
We present here the third published case of palmoplantar orthokeratotic filiform hyperkeratosis of particular clinical interest because of associated Darier's disease. We propose a classification of filiform hyperkeratosis in three groups on the basis of the topography (i.e. palmar and plantar, disseminated with palmoplantar sparing and linear) and the histology (i.e. porokeratosis or orthokeratosis) of the lesions. This keratinization disorder does not seem to be a specific disease entity but rather a syndrome secondary to various disorders.
我们在此呈现第三例已发表的掌跖正角化性丝状角化过度病例，因其与 Darier 病相关而具有特殊的临床意义。我们基于病变的部位（即掌跖部、泛发性且不累及掌跖部以及线状）和组织学特征（即汗孔角化病或正角化病），提出将丝状角化过度分为三组。这种角化异常似乎并非一种特定的疾病实体，而是继发于各种疾病的一种综合征。
