Almazán-Fernández Francisco Manuel, Hernández-Gil Jesús, López Carmen, Macías José P, Naranjo Ramón
Hospital Clínico San Cecilio, Granada, Granada, Spain.
Dermatol Online J. 2009 Oct 15;15(10):12.
Palmar filiform parakeratotic hyperkeratosis (PFPH) is a rare dermatosis; hyperkeratotic lesions appear as small spines on the palms and/or soles. Palmar filiform parakeratotic hyperkeratosis has been associated with a variety of malignant tumors and endocrine disorders, although these associations have not been fully demonstrated. We report two new cases of this entity without systemic pathology associated.
掌部丝状不全角化性角化过度症（PFPH）是一种罕见的皮肤病；角化过度性皮损表现为手掌和/或足底的小棘状物。掌部丝状不全角化性角化过度症与多种恶性肿瘤和内分泌紊乱有关，尽管这些关联尚未得到充分证实。我们报告两例无相关系统性病变的该疾病新病例。
