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非甾体抗炎药所致空肠和结肠隔膜病：2例报告

Non-steroidal anti-inflammatory drug-induced jejunal and colonic diaphragm disease: a report of two cases.

作者信息

Fellows I W, Clarke J M, Roberts P F

机构信息

West Norwich Hospital.

出版信息

Gut. 1992 Oct;33(10):1424-6. doi: 10.1136/gut.33.10.1424.

DOI:10.1136/gut.33.10.1424
PMID:1446874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1379618/
Abstract

Two patients with intestinal submucosal diaphragm disease associated with non-steroidal anti-inflammatory drugs are presented. The jejunum was affected in one, and in the other the ascending colon. Most previously reported cases have shown ileal disease and no case to date has shown involvement of the colon. The reasons for the localisation of these diaphragms remain unclear.

摘要

本文报告了2例与非甾体抗炎药相关的肠黏膜下隔膜病患者。其中1例空肠受累，另1例升结肠受累。此前报道的大多数病例显示为回肠疾病，迄今为止尚无结肠受累的病例。这些隔膜的定位原因尚不清楚。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/122c/1379618/6ee3a6d7accc/gut00577-0159-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/122c/1379618/faa3fa793d68/gut00577-0158-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/122c/1379618/ccfc84c3d987/gut00577-0158-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/122c/1379618/80d7a09ca03d/gut00577-0159-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/122c/1379618/6ee3a6d7accc/gut00577-0159-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/122c/1379618/faa3fa793d68/gut00577-0158-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/122c/1379618/ccfc84c3d987/gut00577-0158-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/122c/1379618/80d7a09ca03d/gut00577-0159-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/122c/1379618/6ee3a6d7accc/gut00577-0159-b.jpg

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1
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Gut. 1992 Oct;33(10):1424-6. doi: 10.1136/gut.33.10.1424.
2
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Severe enteropathy with villous atrophy in prolonged mefenamic acid users - a currently under-recognized in previously well-recognized complication: Case report and review of literature.长期使用甲芬那酸患者出现伴有绒毛萎缩的严重肠病——一种此前未被充分认识的公认并发症：病例报告及文献综述
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A Curious Case of Intestinal Diaphragm Disease Unmasked by Perforation of a Duodenal Ulcer.

本文引用的文献

1
Ulceration and stricture of the jejunum in a patient on long-term indomethacin therapy.一名长期接受吲哚美辛治疗的患者出现空肠溃疡和狭窄。
Am J Gastroenterol. 1973 Feb;59(2):162-9.
2
Diaphragm disease: pathology of disease of the small intestine induced by non-steroidal anti-inflammatory drugs.膈膜病：非甾体抗炎药所致小肠疾病的病理学
J Clin Pathol. 1988 May;41(5):516-26. doi: 10.1136/jcp.41.5.516.
3
Clinicopathological features of nonsteroidal antiinflammatory drug-induced small intestinal strictures.
一例因十二指肠溃疡穿孔而被揭示的罕见肠隔膜疾病病例
Case Rep Med. 2017;2017:5048345. doi: 10.1155/2017/5048345. Epub 2017 Mar 27.
4
COX-2 inhibitory NSAID-induced multiple stenosis in the small intestine diagnosed by double-balloon endoscopy.通过双气囊内镜诊断的COX-2抑制性非甾体抗炎药诱发的小肠多发狭窄
Nagoya J Med Sci. 2016 Aug;78(3):323-8.
5
Special diaphragm-like strictures of small bowel unrelated to non-steroidal anti-inflammatory drugs.非甾体类抗炎药相关的小肠特殊隔膜样狭窄。
World J Gastroenterol. 2011 Aug 21;17(31):3596-604. doi: 10.3748/wjg.v17.i31.3596.
6
Present status and strategy of NSAIDs-induced small bowel injury.非甾体抗炎药诱导的小肠损伤的现状与策略。
J Gastroenterol. 2009;44(9):879-88. doi: 10.1007/s00535-009-0102-2. Epub 2009 Jul 1.
7
Capsule endoscopic diagnosis of nonsteroidal antiinflammatory drug-induced enteropathy.胶囊内镜诊断非甾体抗炎药所致肠病
J Gastroenterol. 2009;44 Suppl 19:64-71. doi: 10.1007/s00535-008-2248-8. Epub 2009 Jan 16.
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[NSAID-colonopathy].[非甾体抗炎药相关性结肠病]
Pathologe. 2006 Feb;27(1):65-72. doi: 10.1007/s00292-005-0810-1.
9
Strictures, diaphragms, erosions or ulcerations of ischemic type in the colon should always prompt consideration of nonsteroidal anti-inflammatory drug-induced lesions.结肠中出现的狭窄、隔膜、缺血型糜烂或溃疡，应始终促使人们考虑非甾体抗炎药引起的病变。
World J Gastroenterol. 2005 Oct 7;11(37):5828-33. doi: 10.3748/wjg.v11.i37.5828.
10
Non-specific multiple ulcers of the small intestine unrelated to non-steroidal anti-inflammatory drugs.与非甾体抗炎药无关的小肠非特异性多发性溃疡
J Clin Pathol. 2004 Nov;57(11):1145-50. doi: 10.1136/jcp.2003.015735.
Gastroenterology. 1988 Apr;94(4):1070-4. doi: 10.1016/0016-5085(88)90568-9.
4
Ulcerations of the colon associated with naproxen and acetylsalicylic acid treatment.与萘普生和阿司匹林治疗相关的结肠溃疡
Gastrointest Endosc. 1986 Jun;32(3):242-4. doi: 10.1016/s0016-5107(86)71824-5.
5
The changing gastrointestinal side effect profile of non-steroidal anti-inflammatory drugs. A new approach for the prevention of a new problem.非甾体抗炎药不断变化的胃肠道副作用情况。预防新问题的新方法。
Scand J Gastroenterol Suppl. 1989;163:56-64. doi: 10.3109/00365528909091176.
6
Non-steroidal anti-inflammatory drug-induced disease in the distal ileum and large bowel.
Scand J Gastroenterol Suppl. 1989;163:48-55. doi: 10.3109/00365528909091175.
7
Ileocolonoscopy in seronegative spondylarthropathy.
Gastroenterology. 1989 Feb;96(2 Pt 1):339-44. doi: 10.1016/0016-5085(89)91557-6.
8
Do non-steroidal anti-inflammatory drugs increase colonic permeability?非甾体抗炎药会增加结肠通透性吗？
Gut. 1991 Jan;32(1):66-9. doi: 10.1136/gut.32.1.66.