Hems T E, Glasby M A
University of Edinburgh Medical School, Scotland.
J Bone Joint Surg Br. 1992 Nov;74(6):918-22. doi: 10.1302/0301-620X.74B6.1447258.
An experimental model was established to investigate the possibility of repairing cervical nerve roots damaged above the dorsal root ganglion, as occurs in traction injuries of the brachial plexus. In four sheep the C6 root was divided and repaired within the dura using freeze-thawed muscle grafts. Recovery was assessed after eight months by electrophysiology and histology. Action potentials were recorded distal to the grafts in all four sheep, indicating regeneration of motor fibres. Histological examination showed regenerated fibres in the ventral roots below the grafts in all cases. These fibres could be traced distally to the brachial plexus. There was no evidence of recovery of dorsal roots.
建立了一个实验模型，以研究修复臂丛神经牵拉伤中出现的背根神经节上方受损的颈神经根的可能性。在四只绵羊中，将C6神经根切断，并使用冻融肌肉移植物在硬脊膜内进行修复。八个月后通过电生理学和组织学评估恢复情况。在所有四只绵羊的移植物远端均记录到动作电位，表明运动纤维发生了再生。组织学检查显示，所有病例中移植物下方的腹侧神经根均有再生纤维。这些纤维可向远端追踪至臂丛神经。没有证据表明背根神经有恢复。
