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PCR detection of HIV proviral DNA in the brain of an asymptomatic HIV-positive patient.

作者信息

Sinclair E, Gray F, Scaravilli F

出版信息

J Neurol. 1992 Oct;239(8):469-70. doi: 10.1007/BF00856814.

DOI:10.1007/BF00856814
PMID:1447577
Abstract
摘要

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PCR detection of HIV proviral DNA in the brain of an asymptomatic HIV-positive patient.在一名无症状HIV阳性患者大脑中进行HIV前病毒DNA的PCR检测。
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本文引用的文献

1
Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain.喹啉酸:一种在大鼠脑中产生轴突保留性损伤的内源性代谢物。
Science. 1983 Jan 21;219(4582):316-8. doi: 10.1126/science.6849138.
2
Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome.获得性免疫缺陷综合征患者循环中恶病质素/肿瘤坏死因子水平升高。
Am J Med. 1988 Sep;85(3):289-91. doi: 10.1016/0002-9343(88)90576-1.
3
Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro.肿瘤坏死因子在体外介导髓鞘和少突胶质细胞损伤。
感染淋巴细胞和大脑的1型人类免疫缺陷病毒基因组的镶嵌结构:区域种群进化过程中频繁发生体内重组事件的证据。
J Virol. 1999 Oct;73(10):8720-31. doi: 10.1128/JVI.73.10.8720-8731.1999.
4
Programmed cell death in brains of HIV-1-positive AIDS and pre-AIDS patients.
Acta Neuropathol. 1996;91(2):169-73. doi: 10.1007/s004010050409.
5
PCR detection of HIV proviral DNA (gag) in the brains of patients with AIDS: comparison between results using fresh frozen and paraffin wax embedded specimens.艾滋病患者大脑中HIV前病毒DNA(gag)的聚合酶链反应检测:新鲜冷冻标本与石蜡包埋标本检测结果的比较
J Clin Pathol. 1994 Nov;47(11):990-4. doi: 10.1136/jcp.47.11.990.
Ann Neurol. 1988 Apr;23(4):339-46. doi: 10.1002/ana.410230405.
4
Intrathecal synthesis of antibodies to HTLV-III in patients without AIDS or AIDS related complex.在无艾滋病或艾滋病相关综合征患者中,鞘内合成针对人类嗜T淋巴细胞病毒III型的抗体。
Br Med J (Clin Res Ed). 1986 May 10;292(6530):1231-4. doi: 10.1136/bmj.292.6530.1231.
5
Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome.从与获得性免疫缺陷综合征相关的神经综合征患者的脑脊液和神经组织中分离出人类嗜T淋巴细胞病毒III型。
N Engl J Med. 1985 Dec 12;313(24):1493-7. doi: 10.1056/NEJM198512123132401.
6
Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide.HIV包膜蛋白对神经元细胞的杀伤作用及其通过血管活性肠肽的预防作用。
Nature. 1988 Oct 13;335(6191):639-42. doi: 10.1038/335639a0.
7
High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients.艾滋病痴呆患者脑组织中高水平的未整合HIV-1 DNA。
Nature. 1990 Jan 4;343(6253):85-9. doi: 10.1038/343085a0.
8
Human immunodeficiency virus-infected individuals contain provirus in small numbers of peripheral mononuclear cells and at low copy numbers.人类免疫缺陷病毒感染个体的少量外周血单个核细胞中含有前病毒,且拷贝数较低。
J Virol. 1990 Feb;64(2):864-72. doi: 10.1128/JVI.64.2.864-872.1990.
9
Amplification of HIV-1 provirus from cerebrospinal fluid and its correlation with neurologic disease.从脑脊液中扩增HIV-1前病毒及其与神经疾病的相关性。
J Infect Dis. 1990 Jun;161(6):1068-72. doi: 10.1093/infdis/161.6.1068.
10
AIDS dementia may be linked to metabolite of tryptophan.艾滋病痴呆可能与色氨酸的代谢物有关。
JAMA. 1990 Jul 18;264(3):305-6.