伯氏考克斯氏体合成丝氨酸。
Synthesis of serine by Coxiella burnetii.
作者信息
MYERS W F, PARETSKY D
出版信息
J Bacteriol. 1961 Nov;82(5):761-3. doi: 10.1128/jb.82.5.761-763.1961.
Abstract
Myers, W. F. (University of Kansas, Lawrence) and D. Paretsky. Synthesis of serine by Coxiella burnetii. J. Bacteriol. 82:761-763. 1961.-Enzyme preparations from suspensions of purified Coxiella burnetii are capable of synthesizing serine from formaldehyde and glycine-2-C(14) in the presence of tetrahydrofolic acid. Evidence for the reaction is obtained by isolating and identifying radioactive serine and serine derivatives. The data suggest a role for folic acid in these rickettsiae, and extend the knowledge of host-independent biosynthetic competencies of these highly parasitic microorganisms.
摘要
迈尔斯，W.F.（堪萨斯大学，劳伦斯分校）和D.帕雷茨基。伯氏考克斯氏体合成丝氨酸。《细菌学杂志》82:761 - 763。1961年。-从纯化的伯氏考克斯氏体悬浮液中制备的酶制剂，在四氢叶酸存在的情况下，能够由甲醛和甘氨酸 - 2 - C¹⁴合成丝氨酸。通过分离和鉴定放射性丝氨酸及丝氨酸衍生物获得了该反应的证据。这些数据表明叶酸在这些立克次氏体中发挥作用，并扩展了对这些高度寄生微生物不依赖宿主的生物合成能力的认识。
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