Storrie-Baker H J, Novotny M F, Crowne D P
Department of Psychology, University of Waterloo, Ontario, Canada.
Pharmacol Biochem Behav. 1992 Nov;43(3):795-7. doi: 10.1016/0091-3057(92)90410-h.
Studies of rotational behavior in female rats have investigated Fischer, Sprague-Dawley, Madison, WI, and Holtzman strains. The present study of amphetamine-induced rotational preference looked at the most widely used of the pigmented strains, Long-Evans hooded rats, examining rotation in females and comparing rotational magnitude and direction to males of the same strain. We corroborate in Long-Evans animals the greater rotation of females, but our findings oppose the right-sided female and left-sided male rotational preferences reported in earlier studies. Only female rats in this experiment had a significant directional bias, and it was to the left. This result strongly points to the importance of strain in the lateralization expressed by rotation.
对雌性大鼠旋转行为的研究涉及Fischer、Sprague-Dawley、威斯康星州麦迪逊以及Holtzman品系。本项关于苯丙胺诱导旋转偏好的研究关注了使用最为广泛的有色品系——Long-Evans有帽大鼠，研究了雌性大鼠的旋转情况，并将旋转幅度和方向与同一品系的雄性大鼠进行比较。我们在Long-Evans动物中证实了雌性大鼠旋转更多，但我们的研究结果与早期研究中报道的雌性偏向右侧、雄性偏向左侧的旋转偏好相反。在本实验中，只有雌性大鼠存在显著的方向偏好，且是偏向左侧。这一结果有力地表明了品系在旋转所表现出的偏侧化中的重要性。
