PIPER D W, STIEL M C
Gut. 1962 Mar;3(1):65-9. doi: 10.1136/gut.3.1.65.
The effect of anticholinergic agents-atropine, propantheline, oxyphencyclimine, and propionyl atropine methyl nitrate-on silva flow and on hypoglycaemic stimulated gastric secretion has been studied. The acid secretion of the nervous phase of gastric secretion was inhibited by anticholinergic drugs. They influenced gastric secretion to a greater extent than saliva flow. Both propantheline and oxyphencyclimine have a selective action on the stomach superior to atropine. Propionyl atropine methyl nitrate appears to have only weak anticholinergic activity in the dose recommended and is not superior to atropine.
已经研究了抗胆碱能药物——阿托品、溴丙胺太林、羟苯环铵和硝甲阿托品丙酸酯——对唾液分泌和低血糖刺激的胃液分泌的影响。抗胆碱能药物抑制了胃液分泌神经期的胃酸分泌。它们对胃液分泌的影响比唾液分泌更大。溴丙胺太林和羟苯环铵对胃的选择性作用优于阿托品。在推荐剂量下，硝甲阿托品丙酸酯似乎仅具有微弱的抗胆碱能活性，并不优于阿托品。
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