Davidowa H, Albrecht D
Institute of Physiology, School of Medicine, Charité, Humboldt-University, Berlin, FRG.
Behav Brain Res. 1992 Sep 28;50(1-2):127-33. doi: 10.1016/s0166-4328(05)80294-3.
Single unit activity was recorded from the ventral part of the lateral geniculate nucleus (vLGN) in rats anaesthetized with urethane. Most of the cells located laterally in the nucleus were excited by light. The studied vLGN neurones did not respond to electrical stimulation of the tail, but about half of them changed their response to light significantly when the light flash was paired with the electrical stimulation. When the tail stimulus preceded the light, the changes consisted in a pronounced facilitation of flash-evoked activity. When the electrical stimulus was applied after the flash in a forward conditioning paradigm, facilitations were less pronounced and responses of some neurones were suppressed. These results are in contrast to those of similar experiments on the dorsal LGN, neurones of which were mainly facilitated by the conditioning paradigm. Thus, light-evoked activity of ventral geniculate cells can be enhanced by arousal-related processes.
在使用乌拉坦麻醉的大鼠中，记录外侧膝状体核腹侧部分（vLGN）的单单位活动。位于该核外侧的大多数细胞受到光刺激会兴奋。所研究的vLGN神经元对尾部的电刺激无反应，但当闪光与电刺激配对时，约一半的神经元对光的反应发生显著变化。当尾部刺激先于光刺激时，变化表现为闪光诱发活动的明显易化。当前向条件化范式中在闪光后施加电刺激时，易化作用不那么明显，并且一些神经元的反应受到抑制。这些结果与在背侧LGN上进行的类似实验结果相反，背侧LGN的神经元主要通过条件化范式得到易化。因此，腹侧膝状体细胞的光诱发活动可通过与觉醒相关的过程增强。
