French C R, Sefton A J, Mackay-Sim A
Exp Brain Res. 1985;57(3):471-9. doi: 10.1007/BF00237834.
Two-shock inhibition, a feature of 98 of 100 P cells recorded in the dorsal lateral geniculate nucleus of the normal rat, was not observed in 91 of 140 geniculate cells after an electrolytic lesion had been made in the adjacent visually responsive thalamic reticular nucleus. Nine geniculate cells recorded both before and after a reticular lesion had their initial inhibition abolished or substantially reduced after the lesion. The reticular lesion eliminated the bursts of spikes which normally terminate periods of inhibition following electrical or photic stimulation but caused no other changes in receptive field organization of geniculate cells. We conclude that the visually responsive region of the thalamic reticular nucleus in the rat is responsible for the profound two-shock inhibition and for the post-inhibitory bursts which are normal properties of relay cells of the dorsal lateral geniculate nucleus.
双脉冲抑制是正常大鼠背侧外侧膝状核中记录到的100个P细胞中的98个细胞所具有的特征，而在相邻的视觉反应性丘脑网状核进行电解损伤后，140个膝状核细胞中的91个未观察到双脉冲抑制现象。在网状核损伤前后均有记录的9个膝状核细胞，其初始抑制在损伤后消失或显著减弱。网状核损伤消除了通常在电刺激或光刺激后终止抑制期的一连串尖峰，但未引起膝状核细胞感受野组织的其他变化。我们得出结论，大鼠丘脑网状核的视觉反应区域负责深度双脉冲抑制以及抑制后爆发，而这是背侧外侧膝状核中继细胞的正常特性。
