Colmegna Ines, Rodriguez-Barradas Maria, Rauch Ronald, Clarridge Jill, Young Edward J
Medical Service, Veterans Affairs Medical Center, Houston, TX 77030, USA.
Am J Med Sci. 2003 Sep;326(3):152-5. doi: 10.1097/00000441-200309000-00010.
Thoracic actinomycosis can resemble bronchogenic carcinoma in its clinical presentation and radiographic appearance. We report a case of pulmonary actinomycosis caused by Actinomyces meyeri in which hematogenous dissemination caused multiple brain abscesses resembling metastatic lung cancer. The correct diagnosis was made by thin-needle aspiration of a pleura-based lung mass. The pathogen isolated was further identified with the use of 16S rDNA sequencing. Antibiotic therapy resulted in rapid improvement of the lung lesion; however, the brain lesions required surgical drainage. Antibiotics were continued for more than a year before magnetic resonance images showed complete resolution of the cerebral abscesses.
胸段放线菌病在临床表现和影像学表现上可能类似于支气管源性癌。我们报告一例由迈耶放线菌引起的肺放线菌病病例，其中血行播散导致多个脑脓肿，类似于转移性肺癌。通过对胸膜下肺肿块进行细针穿刺活检做出了正确诊断。分离出的病原体通过16S rDNA测序进一步鉴定。抗生素治疗使肺部病变迅速改善；然而，脑部病变需要手术引流。在磁共振成像显示脑脓肿完全消退之前，抗生素持续使用了一年多。
