精神分裂症患者脑电图的物理特征。

Physical aspects of the EEG in schizophrenics.

作者信息

Elbert T, Lutzenberger W, Rockstroh B, Berg P, Cohen R

机构信息

Institute for Experimental Audiology, University of Münster, Germany.

出版信息

Biol Psychiatry. 1992 Oct 1;32(7):595-606. doi: 10.1016/0006-3223(92)90072-8.

DOI:10.1016/0006-3223(92)90072-8

PMID:1450286

Abstract

Physical and dynamic aspects of the electroencephalogram (EEG) were evaluated in 12 schizophrenic patients and 12 matched healthy control subjects by means of two descriptive measures proposed by Hjorth (complexity and mobility) and by a nonlinear measure, dimensional complexity. These measures were compared to power spectra analyses. EEG was recorded from frontal, central, and parietal leads under resting conditions (eyes open and eyes closed) for 12 epochs each of 25 sec. Patients showed the expected increased activity in the 1-7 Hz band and, furthermore, a scalp distribution of dimensional complexity and Hjorth complexity opposite to the distribution in controls: in patients dimensional complexity yielded higher values at frontal (Fz) than central (Cz) leads, whereas the resemblance to sinusoidal waveshape (Hjorth complexity) was larger at Fz than Cz. Results indicate more dynamic complexity or variables determining the dynamics of brain processes in frontal areas in patients.

摘要

通过 Hjorth 提出的两种描述性测量方法（复杂度和移动性）以及一种非线性测量方法——维度复杂度，对 12 名精神分裂症患者和 12 名匹配的健康对照受试者的脑电图（EEG）的物理和动态方面进行了评估。将这些测量方法与功率谱分析进行了比较。在静息条件下（睁眼和闭眼），从额叶、中央和顶叶导联记录 EEG，每个导联记录 12 个 epoch，每个 epoch 持续 25 秒。患者在 1-7Hz 频段表现出预期的活动增加，此外，维度复杂度和 Hjorth 复杂度的头皮分布与对照组相反：在患者中，额叶（Fz）导联的维度复杂度值高于中央（Cz）导联，而与正弦波形的相似性（Hjorth 复杂度）在 Fz 导联比 Cz 导联更大。结果表明患者额叶区域大脑过程动力学的动态复杂度或决定动力学的变量更多。