Mousavi Seyed Ali, Malerød Lene, Berg Trond, Kjeken Rune
Department of Biology, University of Oslo, P.O. Box 1050, Blindern, N-0316 Oslo, Norway.
Biochem J. 2004 Jan 1;377(Pt 1):1-16. doi: 10.1042/BJ20031000.
The process by which clathrin-coated vesicles are produced involves interactions of multifunctional adaptor proteins with the plasma membrane, as well as with clathrin and several accessory proteins and phosphoinositides. Here we review recent findings highlighting new insights into mechanisms underlying clathrin-dependent endocytosis.
网格蛋白包被小泡的产生过程涉及多功能衔接蛋白与质膜、网格蛋白以及几种辅助蛋白和磷酸肌醇的相互作用。在此,我们综述了近期的研究发现,这些发现突出了对网格蛋白依赖性内吞作用潜在机制的新见解。