Bradley Gemma L, Leevers Sally J
BioMed Central, Middlesex House, 34-42 Cleveland Street, W1T 4LB, London, United Kingdom.
Cell. 2003 Sep 19;114(6):656-8. doi: 10.1016/s0092-8674(03)00721-9.
The mechanisms by which animals coordinate the growth of different tissues in response to nutrient levels is poorly understood. In this issue of Cell, Colombani et al. demonstrate that amino acid-responsive TOR signaling in the Drosophila fat body modulates insulin signaling and growth in peripheral tissues.
动物如何根据营养水平协调不同组织生长的机制仍知之甚少。在本期《细胞》杂志中,科隆巴尼等人证明,果蝇脂肪体中对氨基酸作出反应的TOR信号传导调节外周组织中的胰岛素信号传导和生长。