Suga Kazuyoshi, Ogasawara Nobuhiko, Matsunaga Naofumi, Sugio Yoshitsugu, Shimizu Ryouichi
Department of Radiology, Yamaguchi University School of Medicine, Ube, Japan.
Clin Nucl Med. 2003 Oct;28(10):827-33. doi: 10.1097/01.rlu.0000090942.53156.61.
Diffuse pulmonary microvascular arteriovenous communication developed in an 8-year-old girl with a patent ductus venosus. Tc-99m macroaggregated albumin (MAA) pulmonary perfusion scintigraphy with total-body imaging demonstrated multiple lung perfusion deficits and abnormal tracer uptake in systemic organs with hepatic radioactivity greater than the kidneys, suggesting the presence of right-to-left shunt and abnormal hepatic hemodynamics. I-123 iodoamphetamine transrectal portal scintigraphy revealed a large portosystemic venous shunt. The follow-up Tc-99m MAA perfusion scans after banding of the patent ductus venosus revealed partial improvement of the perfusion deficits and right-to-left shunt, indicating the possible reversibility of this pulmonary shunt complication.
一名患有静脉导管未闭的8岁女孩出现了弥漫性肺微血管动静脉分流。锝-99m大颗粒聚合白蛋白（MAA）肺灌注闪烁扫描及全身显像显示，肺部存在多处灌注缺损，全身各器官有异常示踪剂摄取，肝脏放射性高于肾脏，提示存在右向左分流及异常的肝脏血流动力学。碘-123碘安非他明经直肠门静脉闪烁扫描显示存在巨大的门体静脉分流。对静脉导管未闭进行结扎后，随访的锝-99m MAA灌注扫描显示灌注缺损及右向左分流部分改善，表明这种肺部分流并发症可能具有可逆性。
