Uchino Akira, Yuzuriha Takefumi, Murakami Masaru, Endoh Koichi, Hiejima Shigeto, Koga Hiroshi, Kudo Sho
Department of Radiology, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan.
Neuroradiology. 2003 Dec;45(12):877-80. doi: 10.1007/s00234-003-1095-9. Epub 2003 Sep 24.
Central pontine myelinolysis (CPM) is one of the serious neurological complications of alcoholism. This study evaluated magnetic resonance images of sequelae of CPM. Approximately 600 alcoholic patients were examined by a 1.0-T magnetic resonance imaging device, and 11 patients were retrospectively found to have a central pontine lesion, a presumed sequela of CPM. The lesions had various shapes and most were cavitary. In 3 of the 11 patients bilateral symmetrical oval lesions were faintly visible in the middle cerebellar peduncles. These middle cerebellar peduncular lesions were diagnosed as having Wallerian degeneration of the pontocerebellar tract secondary to CPM.
中央桥脑髓鞘溶解症(CPM)是酒精中毒严重的神经并发症之一。本研究评估了CPM后遗症的磁共振成像。约600名酒精中毒患者接受了1.0-T磁共振成像设备检查,回顾性发现11例患者有中央桥脑病变,推测为CPM后遗症。病变形状各异,多数为空洞性。11例患者中有3例在小脑中脚可见双侧对称的椭圆形淡薄病灶。这些小脑中脚病灶被诊断为继发于CPM的桥小脑束华勒氏变性。