Faller G, Borchard F, Ell C, Seitz G, Stolte M, Walch A, Rüschoff J
Institute of Pathology, University of Erlangen-Nuremberg, Krankenhausstrasse 8-10, 91054, Erlangen, Germany.
Virchows Arch. 2003 Nov;443(5):597-601. doi: 10.1007/s00428-003-0894-z. Epub 2003 Sep 24.
There are a number of difficulties regarding the diagnosis of Barrett's mucosa and the varying grades of neoplasia that may be associated with it. It was, therefore, the aim of a consensus conference of the Working Group for Gastroenterological Pathology within the German Society of Pathology to achieve standardisation regarding the following issues: definition and diagnostic criteria for Barrett's mucosa and its discrimination from intestinal metaplasia of the cardia, diagnostic criteria for intraepithelial neoplasia, number of biopsies necessary to establish the diagnosis, significance of additional immunohistochemical and/or molecular methods as well as importance of a second opinion in the diagnosis of intraepithelial neoplasia.
关于巴雷特黏膜的诊断以及可能与之相关的不同程度瘤变存在诸多困难。因此,德国病理学会胃肠病病理工作组共识会议的目的是就以下问题实现标准化:巴雷特黏膜的定义和诊断标准及其与贲门肠化生的鉴别、上皮内瘤变的诊断标准、确立诊断所需的活检数量、额外免疫组化和/或分子方法的意义以及上皮内瘤变诊断中二次诊断意见的重要性。