Bachar Gil N, Cohen Maya, Belenky Alexander, Atar Eli, Gideon Shafir
Department of Radiology, Rabin Medical Center, Petah Tiqva, Israel.
J Ultrasound Med. 2003 Sep;22(9):879-82; quiz 883-5. doi: 10.7863/jum.2003.22.9.879.
To determine whether the size of the extrahepatic bile duct increases with age in adults.
We prospectively collected data on 251 patients aged 20 years or older who underwent abdominal sonography. None of the patients had a history of liver, gallbladder, biliary, or pancreatic disease or surgery. The extrahepatic bile duct was measured at 3 locations: in the porta hepatis, in the most distal aspect of the head of the pancreas, and midway between these points. Least squares linear regression was used to correlate patient age and the size of the extrahepatic bile duct.
There were 126 men and 125 women aged 20 to 94 years (mean +/- SD, 52.5 +/- 17.63 years). Twelve percent of the study population were younger than 30 years, and 12% were older than 80 years. The mean diameters of the common bile duct in the 3 locations were as follows: proximal, 3.39 +/- 1.14 mm; middle, 3.72 +/- 1.28 mm; and distal, 4.28 +/- 1.18 mm. The overall mean for all measures was 3.66 +/- 1.15 mm. The width of the common bile duct ranged from 1.0 to 8.6 mm. There was a significant correlation between common bile duct size and age (r = 0.535; P < .001). Mean common bile duct sizes were 3.128 +/- 0.862 mm in the patients younger than 50 years and 4.19 +/- 1.15 mm in the patients older than 50 years (P < .001 by independent t test for equality of means). We have found that the duct gradually dilated 0.04 mm/y.
This study revealed an age-dependent change in the diameter of the extrahepatic bile duct. We suggest that the upper normal limit of the duct in elderly persons be set at 8.5 mm.
确定成人肝外胆管的大小是否随年龄增长而增加。
我们前瞻性收集了251例年龄在20岁及以上接受腹部超声检查患者的数据。所有患者均无肝脏、胆囊、胆管或胰腺疾病史或手术史。在3个位置测量肝外胆管：肝门处、胰头最远端以及这两点之间的中点。采用最小二乘线性回归分析患者年龄与肝外胆管大小之间的相关性。
研究对象包括126名男性和125名女性，年龄在20至94岁之间（平均±标准差，52.5±17.63岁）。12%的研究人群年龄小于30岁，12%的人群年龄大于80岁。胆总管在3个位置的平均直径如下：近端，3.39±1.14mm；中间，3.72±1.28mm；远端，4.28±1.18mm。所有测量值的总体平均值为3.66±1.15mm。胆总管宽度范围为1.0至8.6mm。胆总管大小与年龄之间存在显著相关性（r = 0.535；P < .001）。年龄小于50岁患者的胆总管平均大小为3.128±0.862mm，年龄大于50岁患者的胆总管平均大小为4.19±1.15mm（通过独立样本t检验比较均值，P < .001）。我们发现胆管每年逐渐扩张0.04mm。
本研究揭示了肝外胆管直径随年龄变化的情况。我们建议将老年人胆管的正常上限设定为8.5mm。
