Lagonigro R, Wiener P, Pilla F, Woolliams J A, Williams J L
Roslin Institute, Roslin, Midlothian, Edinburgh, UK.
Anim Genet. 2003 Oct;34(5):371-4. doi: 10.1046/j.1365-2052.2003.01028.x.
An experimental cattle population was screened for polymorphisms in the leptin gene and five SNPs were found in the regions containing the coding sequences. The association of these polymorphisms with feed intake and fat-related traits was evaluated. The results suggest an association between a polymorphism in exon 2, described here for the first time, and feed intake. Individuals with genotype A/T at this position had 19% greater mean feed intake than individuals with genotype A/A. There was also evidence for a link between leptin haplotypes and some fat-related traits.
对一个实验性牛群进行了瘦素基因多态性筛查，在包含编码序列的区域发现了5个单核苷酸多态性（SNP）。评估了这些多态性与采食量和脂肪相关性状之间的关联。结果表明，首次在此描述的外显子2中的一个多态性与采食量之间存在关联。该位置基因型为A/T的个体的平均采食量比基因型为A/A的个体高19%。也有证据表明瘦素单倍型与一些脂肪相关性状之间存在联系。
