Ifuku Hirotoshi, Hirata Shin-Ichi, Nakamura Tamio, Ogawa Hisashi
Department of Physiology, Kumamoto University School of Medicine, 2-2-1 Honjo, Kumamoto 860-0811, Japan.
Neurosci Res. 2003 Oct;47(2):161-75. doi: 10.1016/s0168-0102(03)00194-9.
The correlation between different gustatory areas in the frontal operculum, orbitofrontal area, and insula and the representation of different aspects of cues during a salt-water discrimination delayed GO/NOGO task was studied in a Japanese monkey. Four groups were identified among 169 neurons responding to cues before/after task reversal. Group I (n=78) responded to the physicochemical nature of the cue, Group II (n=8) responded to both the physicochemical nature of the cue and the subsequent behavior, Group III (n=51) (three subgroups) produced discharges related to the subsequent behavior, and Group IV (n=32) produced non-differential responses probably related to attention. The primary gustatory areas (area G and the oral part of area 3) almost exclusively contained Group I neurons, whereas the so-called secondary gustatory areas (the PrCO and area 12) contained most of the Group III neurons. Group IIIc showed discharges accelerating to the LED onset, probably representing preparation for subsequent behavior, and the response differed between the PrCO and area 12. The PrCO also contained Group IV neurons. The primary gustatory areas process pure gustatory signals, whereas the PrCO and area 12 may be involved in gustatory perception, attention, or behavior.
在一只日本猕猴身上，研究了额盖、眶额区和脑岛中不同味觉区域之间的相关性，以及在盐水辨别延迟“执行/不执行”任务期间线索不同方面的表征。在169个对任务反转前后的线索有反应的神经元中，识别出了四组。第一组（n = 78）对线索的物理化学性质有反应，第二组（n = 8）对线索的物理化学性质和随后的行为都有反应，第三组（n = 51）（三个亚组）产生与随后行为相关的放电，第四组（n = 32）产生可能与注意力相关的无差异反应。主要味觉区域（G区和3区的口部）几乎只包含第一组神经元，而所谓的次要味觉区域（前扣带回岛盖部和12区）包含了大部分第三组神经元。第三组c亚组在发光二极管亮起时放电加速，可能代表对随后行为的准备，并且前扣带回岛盖部和12区的反应有所不同。前扣带回岛盖部也包含第四组神经元。主要味觉区域处理纯粹的味觉信号，而前扣带回岛盖部和12区可能参与味觉感知、注意力或行为。
