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睡眠与昼夜节律:睡眠中枢会向生物钟反馈信息吗?

Sleep and circadian rhythms: do sleep centers talk back to the clock?

作者信息

Colwell Christopher S, Michel Stephan

出版信息

Nat Neurosci. 2003 Oct;6(10):1005-6. doi: 10.1038/nn1003-1005.

Abstract

A homeostatic control mechanism that monitors and reacts to the need for sleep has been thought to function independently of the brain's circadian clock in previous studies. Now simultaneous recordings of sleep stages and electrical activity in the suprachiasmatic nucleus in behaving animals reveal feedback from sleep centers to the circadian pacemaker.

摘要

在以往的研究中,一种监测睡眠需求并做出反应的稳态控制机制被认为独立于大脑的昼夜节律时钟发挥作用。现在,对行为动物的睡眠阶段和视交叉上核的电活动进行同步记录,揭示了从睡眠中枢到昼夜节律起搏器的反馈。

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